Tomates

Tomates
Uma das mais conhecidas fontes de Licopeno

quinta-feira, 23 de setembro de 2010

Referências e estudos científicos

O licopeno é um dos antioxidantes mais estudados pela ciência, dada a sua importância na prevenção e combate à diversas patologias.
o site www.scielo.br, uma  referência em publicações de artigos e estudos científicos, respeitado por sua credibilidade e confiabilidade, apresenta diversos estudos científicos e autores de todo o mundo sobre o licopeno:


1. Méndez Filho JD, Rodríguez HGR. Sobre los benefícios de los radicales libres. Rev Med IMSS 1997; 35(4):309-13.        [ Links ]
2. Speisky HC, Jiménez IT. Radicales libres y antioxidantes en la prevención de enfermidades III: evidencias clínico epidemiológicas de los riesgos y beneficios asociados al consumo de antioxidantes en la prevención de enfermidades cardiovasculares. Rev Chil Nutr 2000; 27(3): 314-25.        [ Links ]
3. Papas AM. Diet and antioxidant status. Food Chem Toxicol 1999; 37:999-1007.        [ Links ]
4. Halliwell B, Gutterdge JMC. Antioxidant defenses. In: Free radicals in biology and medicine. 3rd ed. Oxford: Clarenton Press; 1999. p.105-245.        [ Links ]
5. Pool-Zobel BL, Bub A, Müller H, Wollowski I, Rechkemmer G. Consumption of vegetables reduces genetic damage in humans: first results of a human intervention trial with carotenoid-rich foods. Carcinogenesis 1997; 18(9):1847-50.        [ Links ]
6. Bianchi MLP, Antunes LMG. Radicais livres e os principais antioxidantes da dieta. Rev Nutr 1999; 12(2):123-30.        [ Links ]
7. Silva CRM, Naves MMV. Suplementação de vitaminas na prevenção de câncer. Rev Nutr 2001; 14(2):135-43.        [ Links ]
8. Agarwal S, Rao AV. Tomato lycopene and its role in human health and chronic diseases. Canad Med Assoc J 2000; 163(6):739-44.        [ Links ]
9. Halliwell B, Gutterdge JMC. The chemistry of free radicals and, related `reactive species'. In: Free radicals in biology and medicine. 3rd ed. Oxford: Clarenton Press; 1999. p.36-104.        [ Links ]
10. Anderson D. Antioxidant defences against reactive oxygen species causing genetic and other damage. Mut Res 2000; 350(1):103-8.        [ Links ]
11. Ferreira ALA, Matsubara LS. Radicais livres: conceitos, doenças relacionadas, sistema de defesa e estresse oxidativo. Rev Assoc Med Bras 1997; 43(1):61-8.        [ Links ]
12. Cooper KH. Revolução antioxidante. 2.ed. Rio de Janeiro: Record; 1996. p.29-38.        [ Links ]
13. Lucesoli F, Fraga C. Evaluación del estres oxidativo. Antioxid Calid Vida 1995; 1(4):8-13.        [ Links ]
14. Buzzini SRR, Matsudo VKR. Radicais livres, exercício e envelhecimento. Rev Bras Ciências Mov 1990; 4(4):61-85.        [ Links ]
15. Halliwell B, Gutterdge JMC. Free radical, other reactive species and disease. In: Free radicals in biology and medicine. 3rd Oxford: Clarenton Press 1999. p.617-783.        [ Links ]
16. Matés JM, Pérez-Gómez C, Castro IN. Antioxidant enzymes and human diseases. Clin Biochem 1999; 32(8):595-603.        [ Links ]
17. Aust O, Sies H, Stahl W, Polidori MC. Analysis of lipophilic antioxidants in human serum and tissues: tocopherols and carotenoids. J Chromatogr 2001; 936:83-93.        [ Links ]
18. Handelman GJ. The evolving role of carotenoids in human biochemistry. Nutrition 2001; 17: 818-22.        [ Links ]
19. Sies H, Stahl W. Vitamins E and C, beta-carotene, and other carotenoids as antioxidants. Am J Clin Nutr 1995; 62(6):1315-21.        [ Links ]
20. Montero M. Los radicales libres y las defensas antioxidantes: revisión. Ann Fac Med 1996; 57(4):278-81.        [ Links ]
21. Stahl W, Sies H. Carotenoids: occurrence, biochemical activities, and bioavailability. In: Packer L, Hiramatsu M, Yoshikawa T. Antioxidant food suplements in human health. San Diego: Academic Press; 1999. p.183-98.        [ Links ]
22. Olson JA. Carotenoids and human health. Arch Latinoam Nutr 1999; 49(3 Suppl 1):7-11.        [ Links ]
23. Erdman Jr JW, Variable bioavailability of carotenoids from vegetables. Am J Clin Nutr 1999; 70(2):179-80.        [ Links ]
24. Di Mascio P, Kaiser S, Sies S. Lycopene as the most efficiente biological carotenoid singlet oxygen quencher. Arch Biochem Biophys 1989; 274(2):532-8.        [ Links ]
25. Krinsky NI. Carotenoids as antioxidants. Nutrition 2001; 17:815-7.        [ Links ]
26. Arab L, Steck S. Lycopene and cardiovascular disease. Am J Clin Nutr 2000; 71(6):1691-5.        [ Links ]
27. Djuric Z, Powell LC. Antioxidant capacity of lycopene-containing foods. Int J Food Sci Nutr 2001; 52:143-9.        [ Links ]
28. Takeoka GR, Dao L, Flessa S, Gillespie DM, Jewell WT, Huebner B, et al. Processing effects on lycopene content and antioxidant activity of tomatoes. J Agric Food Chem 2001; 49(8): 3713-7.        [ Links ]
29. Giovannucci E. Tomatoes, tomato-based products, lycopene, and cancer: review of the epidemiologic literature. J Natl Cancer Inst 1999; 91(4):317-31.        [ Links ]
30. Gartner C, Stahl W, Sies H. Lycopene is more bioavailable from tomato paste than from fresh tomatoes. Am J Clin Nutr 1997; 66(1):116-22.        [ Links ]
31. Clinton SK, Emenhiser C, Schwartz SJ, Bostwick DG, Williams AW, Erdman JW, Jr. Cis-trans lycopene isomers, carotenoids and retinol in the human prostate. Cancer Epidemiol 1996; 5:823-33.        [ Links ]
32. Willcox JK, Catignani GL, Lazarus S. Tomatoes and cardiovascular health. Crit Rev Food Sci Nutr 2003; 43(1):1-18.        [ Links ]
33. Boileau AC, Merchen NR, Wasson K, Atkinson CA, Erdman JW, Jr. Cis-lycopene is more bioavailable than trans-lycopene in vitro and in vivo in lymph-cannulated ferrets. J Nutr 1999; 129(6):1176-81.        [ Links ]
34. Shi J, Maguer ML. Lycopene in tomatoes: chemical and physical properties affect by food processing. Crit Rev Biotech 2000; 20(4):293-334.        [ Links ]
35. Giovannucci E, Ascherio A, Rimm EB, Stampfer MJ, Colditz GA, Willett WC. Intake of carotenoids and retinol in relation to risk of prostate cancer. J Natl Cancer Inst 1995; 87(3):1767-76.        [ Links ]
36. Boileau TWM, Clinton SK, Erdman Jr JW. Tissue lycopene concentrations and isomer patterns are affected by androgen status and dietary lycopene concentration in male F344 rats. J Nutr 2000; 130:1613-8.        [ Links ]
37. Willis MS, Wians Jr, FH. The role of nutrition in preventing prostate cancer: a review of the proposed mechanism of action of various dietary substances. Clin Chim Acta 2003; 330:57-83.        [ Links ]
38. Shirai T, Asamoto M, Takahashi S, Imaida K. Diet and prostate cancer. Toxicology 2002; 181-2: 89-94.        [ Links ]
39. Tucker G. Nutritional enhancement of plants. Curr Opin Biotechnnol 2003; 14:1-5.        [ Links ]
40. Michaud DS, Feskanich D, Rinn EB, Colditz GA, Speizer FE, Willett WC, et al. Intake of specific carotenoids and risk of lung cancer in 2 prospective US cohorts. Am J Clin Nutr 2000; 72(4):990-7.        [ Links ]
41. Heber D. Colorful cancer prevention: b-carotene, lycopene, and lung cancer. Am J Clin Nutr 2000; 72(4):901-2.        [ Links ]
42. Bohm F, Tinkler JH, Truscott TG. Carotenoids protect against cell membrane damage by the nitrogen dioxide radical. Nat Med 1995; 1:98-9.        [ Links ]
43. Stahl W, Sies H. Lycopene: a biologically important carotenoid for humans? Arch Biochem Biophys 1996; 336(1):1-9.        [ Links ]
44. Rao AV, AGARWAL S. Bioavailability and in vivo antioxidant properties of lycopene from tomato products and their possible role in the prevention of cancer. Nutr Cancer 1998; 31(3):199-203.        [ Links ]
45. Kris-Etherton PM, Hecker KD, Bonanome A, Coval SM, Binkoski AE, Hilpert KF, et al. Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer. Am J Med 2002; 113(9B):71S-88S.        [ Links ]
46. Rao AV, Agarwal S. Role of antioxidant lycopene in câncer and heart disease. J Am Coll Nutr 2000; 19(5):563-9.        [ Links ]
47. Rodriguez-Amaya DB. Latin american food sources of carotenoids. Arch Latinoam Nutr 1999; 49(3 Suppl 1):74-84.        [ Links ]
48. Rao AV, Waseem Z, Agarwal S. Lycopene contents of tomatoes and tomato products and their contribution to dietary lycopene. Food Res Intl 1998; 31:737-41.        [ Links ]
49. Programa de Apoio à Nutrição (NUT). Versão 2.5. CIS/EPM. São Paulo: UNIFESP; 1996.

Nenhum comentário:

Postar um comentário